Ryan Giggs opened the scoring but a double from Carlos Tevez gave City a 2-1 advantage after the first leg of the semi-final, although United went on to reach the final with a 3-1 win at Old Trafford.
We’ve taken a look back at both sides from that day, including some Premier League legends and other cult heroes.
By the end of 2010, Given was replaced by Joe Hart as City’s permanent first-choice goalkeeper and the Republic of Ireland international signed for Aston Villa in 2011.
After a spell with Stoke City, he announced his retirement in 2018 and Given is currently the goalkeeper coach at Derby County.
Zabaleta joined Manchester City a day before Sheikh Mansour’s takeover and spent nine years at the club, making 332 appearances and winning two Premier League titles.
The defender moved to West Ham in 2017 but has admitted that he could return to his former club as a coach after he hangs up his boots.
“Why not? I spent nine years at Man City,” he told The Sun, “it was like a home and my last meeting with (chairman) Khaldoon Al-Mubarak, he said the door will be open for me to come back to Man City in some role, so we will see. It would be special.”
Now 31, Richards came through the youth system at City and played a key role in their Premier League title win in 2011-12.
But he was plagued by persistent knee injuries throughout his career and was released by the club in 2015 before retiring last year after a spell at Aston Villa.
The former Blues defender is now combining work as a pundit with his promotional role at City.
With Micah Richards retiring it feels like the perfect time to show this again pic.twitter.com/nXY4bGirO3
— Stretchy (@Stretchy99) July 26, 2019
The Manchester derby was only Boyata’s third first-team appearance for City, but he was eventually named their young player of the season in 2009-10.
The defender then found it increasingly hard to find a place in the squad at the Etihad and joined Celtic in 2015 before moving to Hertha Berlin in the summer.
Onouha left City in 2012 and after six years with QPR moved to America with Real Salt Lake in 2018.
After signing from Real Sociedad in 2007, Garrido fell out of favour under Mark Hughes but was given another chance by Roberto Mancini.
However, the left-back moved to Lazio in 2010 as Aleksandar Kolarov went in the other direction, and Garrido is currently playing for Real Union in the Spanish second division.
Kompany moved to City in 2008, and the defender – who started in midfield against United – became a vital part of their success over the next 11 years.
The Belgian won four Premier League titles, two FA Cups and four League Cups before he returned to his former club Anderlecht last year to become player-manager.
But the Brussels-based club had an awful start to the season and Kompany gave up managerial duties to focus on being a player.
Vincent Kompany has won Match of the Day's prestigious Goal of the Season competition for his long range screamer against Leicester City.
— Man City | Superbia (@SuperbiaProeIia) May 12, 2019
De Jong was a fan favourite at City, with the midfielder never afraid to get stuck into a challenge.
The 35-year-old had spells at AC Milan, LA Galaxy, Galatasaray, Mainz and Qatari outfit Al Ahli Doha since leaving City in 2012, and he made a domestic transfer to Al-Shahania in July.
Barry played a key role in City’s title win in 2012 before joining Everton a year later, and he then went on to become the Premier League’s all time leading appearance maker.
The veteran midfielder was released by West Brom at the end of last season but rejoined the club in November after recovering from an injury problem.
Barry has now been playing football across three different decades after making his Aston Villa debut in 1998.
FUN FACT 🚨
— Charlton Athletic FC (@CAFCofficial) January 5, 2020
The winger found himself in-and-out of the team under Mancini and joined QPR in 2011, spending four years in London.
Wright-Phillips then had spells in America with New York Red Bulls and Phoenix Rising FC before deciding to call time on his career in August 2019.
Sylvinho spent once season at City before hanging up his boots in 2011 to focus on a career in management. However, the Brazilian was recently sacked by Lyon after a run of one win in nine matches.
Tevez was the most unpopular man in the red half of Manchester after joining their rivals in 2009, and he particularly annoyed United fans that night.
The striker scored both of City’s goals in the 2-1 win and made a point of celebrating in front of a former team-mate.
“My celebration was directed at Gary Neville,” Tevez said after Neville responded by giving him the middle finger. “He acted like a complete boot licker when he said I wasn’t worth £25million, just to suck up to the manager. I don’t know what the hell that idiot is talking about me for. I never said anything about him.”
Benjani struggled for first-team opportunities after the arrival of Tevez and Adebayor and his City contract expired at the end of the 2009-10 season. He had spells with Blackburn and Portsmouth but eventually retired in 2014.
— Man City | Superbia (@SuperbiaProeIia) January 6, 2020
Bellamy fell out of favour at City under Mancini and the forward was loaned out to Cardiff City for the 2010-11 season.
The Welshman made a surprise return to Liverpool in 2012 before spending the last two years of his career back at Cardiff.
Bellamy stepped down from his role as Cardiff’s under-18s coach earlier this year amid allegations of bullying, but he recently reunited with Vincent Kompany to became under-21s coach at Anderlecht.
The goalkeeper spent six years at Old Trafford before announcing his retirement in 2011. However, he came out of retirement at the age of 45 for one game to help his former side VV Noordwijk in 2016.
Van der Sar took on a job as Ajax’s marketing director in 2012 before being promoted to the role of chief executive in 2016
— RedMancunian (@RedMancunian) March 12, 2016
Rafael joined United in 2008 and won three Premier League titles, the FIFA Club World Cup and a League Cup during his seven years at the club.
The right-back lost his place to Antonio Valencia and fell out of favour under Louis Van Gaal, so he moved to Lyon in 2015.
Diouf never got many chances in the first-team and was sold to Hannover 96, but the striker returned to England with Stoke City in 2014.
Evans was another United defender who struggled under Van Gaal and the 31-year-old was sold to West Brom in 2015.
The centre-back rebuilt his career at the Hawthorns before joining Leicester for just £3.5million in 2018 after West Brom were relegated.
“When I came in, I knew he was top class. I’ve seen him grow as a young player and you don’t play for a club like Manchester United unless you’re a top player,” Brendan Rodgers said.
“It’s about him being consistently available because he’s a player that can play at the very top level of football.”
After 15 successful years at United, Brown joined Sunderland in 2011 as he looked for regular playing time and had a five year spell with the Black Cats.
The defender then had a season at Blackburn Rovers before agreeing a deal with Kerala Blasters to play in the Indian Super League in 2017.
Evra joined United in 2006 and won five Premier League titles, three League Cups and a Champions League title in his time with the club.
The left-back signed for Juventus before moving to Marseille, but his contract was terminated after he kicked a fan in the head. Yes, really.
Evra returned to England with West Ham in 2018, but he made just five appearances for the club and announced his retirement in 2019. The 38-year-old has now returned to Old Trafford to complete his coaching badges.
Carrick won a plethora of honours during his 12 years at United and is now part of Ole Gunnar Solskjaer’s coaching staff at Old Trafford.
Fletcher was sidelined for several months when he was diagnosed with chronic bowel disease ulcerative colitis in 2011 but made his comeback in 2012.
The midfielder joined West Brom in 2015 and became a regular in the side before joining Stoke City, but he left the club at the end of the 2018-19 season.
Fletcher has not yet officially retired from playing, but the 35-year-old has been studying for coaching qualifications.
Anderson was once regarded as one of the best young talents in world football, but he never reached his full potential and few supporters were disappointed to see the midfielder leave.
He returned to Brazil with Internacional in 2015 but was released three years later and moved to Adana Demirspor in Turkey before announcing his retirement at the age of 31.
Owen’s United contract expired in 2012, and the striker retired a year later after a brief spell with Stoke City.
Valencia was signed as Cristiano Ronaldo’s replacement and, while he was never able to fill those shoes, was a brilliant signing for the club.
The Ecuadorian spent 10 years at Old Trafford before joining LDU Quito on a free transfer in 2019, and he has already led them to a domestic cup title.
Scholes came out of retirement in 2012 and helped United win their 20th league title before hanging up his boots for the second time and becoming a TV pundit.
Rooney eventually became United’s all-time leading scorer after getting 253 goals in 559 appearances for the club between 2004 and 2017.
The forward returned to boyhood club Everton for the 2017-18 season before moving to America with DC United. He has now returned to England with Derby County as a player-coach.
Rooney gets a assist on his debut for Derby! 🎯 pic.twitter.com/MX0msuSUvb
— ManUnitedZone (@ManUnitedZone_) January 2, 2020
Giggs announced his retirement from football in 2014 after winning 13 Premier League titles, four FA Cups and two Champions Leagues during his 24 years at United.
The legendary midfielder was part of Van Gaal’s coaching staff at Old Trafford, but he departed the club when Jose Mourinho was appointed as the new United manager.
Giggs replaced Chris Coleman as Wales manager in 2018 and the 46-year-old helped his his country qualify for Euro 2020.